To be honest, I've played around 20 hours and I've only done the first main mission with Jackie. Since then all I've done is side missions and explore the city.
I might wait for bugs to be fixed before I progress the main story, will see. I've not suffered any issues or crashes myself, and I've been having a blast.
I think it's a really good game, though not as much of an RPG as I'd hoped. But then I found Fallout 76 to be okay, so what do I know😁