At any weight you can run it's all about pace and distance.
Even 1k at a slow pace of 10 minutes per KM is better than something.
Before this covid i had applied to go on a run leaders course to which got cancelled but we get new runners to the club i run with some are over weight and they come with questions about their weight and running to which i always say it's about your pace and distance and always say start at 1 KM at a really slow pace and built it up little bit at a time when you are comfortable with the distance you start from.
Mostly on my long runs i keep getting blisters on the inside of my foot and toes which could be either my running trainers or the way i run to which i need to see a doctor as the out side of my normal wearing shoes/trainers wear down but with my trainers i own 3 pairs 1 pair is solely for trail running then i have competition/event running then my old pair which do seem to have plenty of life left in them but it stats with them that after 500 km they need to be replaced and i'm on about 900 km with them so only way really to find out is use my event running pair see if i get and blisters.